Greater Manchester Police have closed Stopes Road, Little Lever in Bolton following a Road Traffic collision at 3.30am on Sunday August 1.
Police have advised that the road between will be closed for some time as they work to clear the incident.
Motorists have been told to avoid the area if possible or divert to the A465.
Local buses including Diamond Bus North West services will all be diverted whilst police deal with the road traffic collision.
In a tweet at around 3.40am, Transport for Greater Manchester said the closure likely to go on into later this morning and buses are likely to be diverted.
Scroll down for updates as we get them.